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It should be noted that the studies performed using edited sequences (Emir et al., 2011, Hupfeld et al., 2021, Lally et al., 2016, Suri et al., 2017) used long TEs, and therefore, possible age-related differential changes in T2 relaxation time of GSH relative to the water or creatine quantitation reference could have confounded estimations of age-related concentration differences

In contrast, modified NADs typically require carriers to enter target cells and reach specific intracellular locations

Funding This research was supported by the National Natural Science Foundation of China (No

Ketogenic diet has moderate effects on the fecal microbiota of wild-type mice

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The failure of these antioxidants to seriously modify the toxicity of the herbicide has been attributed mostly to their inability to cross cell membrane barriers and/or to their rapid clearance from cells [3, 4, 6, 7, 10, 11]