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MCT1 is responsible for both influx and efflux of lactate as well as for transport of lactate into the mitochondria and the peroxisomes

T2D is a multifactorial, complex disease and can be controlled by diet modifications, control of physical activity, weight reduction, etc

Without surrounding stress, it gets tagged by Kelch-like ECH-associated protein 1 (Keap1) and then decomposed in the proteasome

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