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Antioxidants protect the fluorescent molecule from oxidative degeneration

doi: 10.1111/j.1753-4887.2004.tb00060.x
The CSNB mutant T94 2.61 I mutant is constitutively active 18,19 but does not show increased dark-state activity compared to the WT 16 , despite it results in extremely long-lived Meta II intermediate 14,18 E134 3.49 Q exhibits 1.5-fold dark-state activity relative to WT and is constitutively active 8,15
Glutathione is a powerful antioxidant that supports detoxification and combats oxidative stress

The lineage here goes back to pramlintide, an earlier amylin analog used in diabetes that had to be injected several times a day

336 The Expression of Pathological Proteins in Skin Biopsies from Patients with Movement Disorders in the MidAsian Population A
