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Description
440 Other oncogenic lncRNAs, including MALAT1, MEG3, NEAT1, and HOTAIR, promote EMT and contribute to the aggressive phenotype of GBM

By blocking tyrosinase, Glutathione reduces melanin production, leading to lighter skin

[DOI] [PubMed] [Google Scholar] 150.Roy S.K., Srivastava R.K., Shankar S
SCFAs activate GPCR41/43 to reduce hepatic cholesterol synthesis, inhibit NF-B-mediated inflammation, and enhance endothelial nitric oxide (NO) production ( / mice, SCFAs reduce aortic plaque area by 3040% ( 3.2 Inflammatory activation: LPS and cytokine cascades Gut barrier disruption (reduced occludin, ZO-1 expression) allows LPS translocation, activating TLR4/NF-B signaling in macrophages and endothelial cells ( 3.3 Vascular dysfunction: endothelial injury and oxidative stress Dysbiosis-derived metabolites (TMAO, LPS) and reduced SCFAs impair endothelial function by decreasing NO bioavailability and increasing reactive oxygen species (ROS) ( 4 Probiotics in atherosclerosis: mechanisms of action Probiotics exert anti-atherosclerotic effects through strain-specific modulation of gut microbiota, metabolic homeostasis, inflammation, and vascular function ( Table 1 )

glabrata has been demonstrated to evade the hosts immune response (261)

+ cluster in aconitase ( The excess accumulation of labile iron in the mitochondria of FRDA patients can react with the mitochondrial reactive oxygen species (ROS) that is inevitably present in these organelles due to occasional leakages of electron(s) from the electron transport chain (Zhao et al., 2019)
