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Oral bioavailability is negligible any oral or peptide spray product claiming IGF-1 LR3 activity via non-injectable routes is not credible

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GHK-Cu has the better-documented delivery mechanism because the peptide portion (GHK) enhances cellular uptake of copper ions

2024;132:112030 Glaser R, Kiecolt-Glaser JK

doi: 10.1093/nar/gkx998
