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The application of AI in CFS diagnosis is developing rapidly: The BioMapAI deep learning model, developed in 2025, has successfully integrated gut microbiome, plasma metabolome and immune cell profiling data from 249 participants, and constructed a microbiome-immune-metabolic interaction network

The experimental setup is depicted (Fig

Glucocorticoid receptor (GR) modulation has been shown to reduce inflammation and glial reactivity in mouse models [259]

doi: 10.1093/jn/129.2.498S 209

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