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Description
Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene

The DisGeNET knowledge platform for disease genomics: 2019 update

The crystal structures of inhibitor-complexed forms also indicate that Gly-473 to Thr-475 forms an oxyanion hole, which interacts with the oxyanion of the tetrahedral intermediate in the transition state

However, the effect of C677T polymorphisms of MTHFR on cognitive function was not significant in normal subjects as a longitudinal cognitive study showed that the MTHFR C677T polymorphism was not associated with cognitive performance at baseline or over 12 years 49

What can we do if these side effects keep us from working

(2.4, 5.1) Renal Failure: Can cause severe, and sometimes fatal, renal failure
