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In this panorama, the recognized role of CoQ 10 as an antioxidant agent endowed with anti-inflammatory properties has been suggested in last years as a promising strategy to be associated with the therapy of ND [5]

Moreover, ATZ markedly elevated malondialdehyde levels, suppressed the activities of endogenous antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase), and downregulated the transcription of key steroidogenic genes ( HSD3B , StAR and CYP11A1 )

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