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doi: 10.1016/j.addbeh.2004.06.020 46 DhaliwalJ

The results indicated that the combination of exercise and nanocurcumin significantly reduced plasma IL-1 and nitric oxide (NO) levels, correlating with improvements in depression scores [240]

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High melanin levels in the body can result from several factors, including genetics, certain medications, prolonged sun exposure, ageing, hormonal changes during pregnancy or menopause, the use of oral contraceptive pills, and underlying health conditions such as Addisons disease, diabetes, or thyroid 1,5
