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Ccl2 and interleukin-6 promote survival of human cd11b+ Peripheral blood mononuclear cells and induce M2-type macrophage polarization

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However, all safety data comes from a single lab, no long-term studies exist, and the FDA cited specific safety concerns (immunogenicity, aggregation, impurities) in its 2023 ban

Foundational studies published prior to 2013, such as those focusing on SCFAs and the brain-gut axis, will also be considered