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The clinical trials of ramucirumab were large-scale, involving multiple continents and countries, and it has been proved that single drug or ramucirumab paclitaxel combination in the treatment of GC can prolong the PFS and OS of patients, thus becoming the standard second-line therapy for GC
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Molecular dynamic simulations Molecular dynamics simulations (MD) are the fundamental tools to identify the stability patterns and stable conformations of synthesized compounds with targeted protein molecules at the active sites
The ectomycorrhizal basidiomycete Laccaria bicolor releases a GH28 polygalacturonase that plays a key role in symbiosis establishment
The aim of GX-G3 development was to extend the drug half-life and eliminate unwanted ADCC or CDC 13,14
