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The chemical structures of flavonoids classify them into several subgroups, including flavones, flavanones, flavanols, isoflavones, the leucoanthocyanidins, anthocyanins, and chalcones (129)

At the same time, it is essential for providing a selective barrier that prevents translocation of harmful substances as well as pathogens and their products from the external environment to the blood stream

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This protein is usually engineered to contain an affinity tag that facilitates its immobilization