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The first change seen is endothelial activation, which is characterized by an aberrant pro-inflammatory and pro-thrombotic phenotype of blood vessel endothelial cells

doi: 10.1016/j.yexcr.2020.111846

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Higher serum Metrnl levels are associated with increased vascular calcification in hemodialysis patients

[DOI] [PMC free article] [PubMed] [Google Scholar] Takada A, Bannai S

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