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B12 deficiency may cause nerve damage, such as numbness and tingling in the hands and feet

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B12 deficiency is also more common among the elderly (7)

There is one Phase I trial registered as NCT02637284 in 2015, intended to enrol forty-two participants, which was subsequently cancelled with no published results [7]

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Because of the small volume syringes available in the U.S., large volume aliquots make larger scale volumization of the buttocks region with CaHA impractical