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Using an AKT activator (SC-79) and an AMPK inhibitor (HY-151361) to simulate the over activation of tumor pathways, we observed a significant increase in the precursor and active forms of SREBP2 (Fig

doi: 10.5045/kjh.2012.47.1.44 17 De KoningCPlantingaMBesselingPBoelensJJNierkensS

This targeted mechanism minimizes the risk of off-target effects and supports the compounds favorable safety profile

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