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Description
Also, those inhibitors that rely on NNMT-catalyzed methylation to be activated add another complexity to the consequence of NNMT inhibition as the consumption of SAM would alter the methylation potential and affect the epigenetic landscape
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Most often, these patients will have mood issues such as depression and bipolar disorders, including anxiety, Obsessive-Compulsive Disorder (OCD), and Attention Deficit Hyperactivity Disorder (ADHD)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Shahripour R.B., Harrigan M.R., Alexandrov A.V
