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Restricting glutamine or glutamine-dependent purine and pyrimidine syntheses promotes human T cells with high FOXP3 expression and regulatory properties

2B, C), confirming that cystine restriction elevates oxidative and ferroptosis stress

Cureus 17:e90459

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Constitutive overexpression of the proto-oncogenes c-myb in Balb/c-3T3 cells increases expression of both IGF-1 and IGF-1R, at least partly through an increased transcriptional activity and in this way abrogates the requirement for IGF-1 in the growing media (Kim et al, 1996)

[DOI] [PubMed] [Google Scholar] 19.Fairweather-Tait S.J., Bao Y., Broadley M.R., Collings R., Ford D., Hesketh J.E., Hurst R