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Data availability Uncropped western blot images are provided in Supplementary Fig

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Timing: Upon waking, 3060 minutes before food or exercise

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However, the body weight of 5A-1MQ-treated obese mice (WD/LD-T group), which was indistinguishable from the other DIO groups at study start, was indistinguishable from the lean control (LD/LD-V) group at study completion (results with FDR correction