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Interestingly, the ability of SeC@PA(+) to eliminate GSH was significantly stronger than that of C@PA(+), indicating that Se was involved in the degradation of GSH after irradiation

ROS mediate oxidative stress through the chemical modification and damage of connective tissue fibers, DNA, proteins, and lipids [99]

[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Ai G, et al

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de Haan JB, Bladier C, Griffiths P, Kelner M, O'Shea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS, Beart PM, Hertzog PJ, Kola I

The PERK-ATF4-CHOP pathway is a central signaling cascade activated in response to ER stress, serving as the cells primary reaction to dysfunction and playing a crucial role in cellular survival