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Elevation of these proteins implies that CSD would trigger ER stress by inducing the unfolded protein response

So what's really going on

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Development 149:dev200750

Catalysis Mediated via Nucleophile Threonine Gamma-glutamyl transpeptidase enzyme catalyzes a two-step reaction, involving cleavage of -glutamyl bond present in -glutamyl compounds like glutathione and glutamine subsequently, followed by transfer of -glutamyl moiety to a water molecule or another amino acid or short peptide (Tate and Meister, 1981)

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the international society for extracellular vesicles and update of the MISEV2014 guidelines