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Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81

developed a red-line Jak2VF-expressing hyperlipidemic erythropoietin receptor Cre mice

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The homogenates were centrifuged at 20,400 g for 20 min at 4 C, and the resulting supernatants were appropriately diluted and used in the assays, which were conducted according to the manufacturers instructions

MAT2A has been proposed as a therapeutic target in tumors with MTAP gene deletion