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Scurvy is a pathological life-threatening condition suffered by people who do not have access to fruits or vegetables for long periods of time

These responses may include mild fatigue, changes in bowel patterns, or minor skin changes as the body increases its detoxification activity

NifB is an S-adenosylmethionine (SAM)-dependent enzyme involved in the formation of an FeS cluster precursor of an ironmolybdenum cofactor (FeMo-co) required for the reconstitution of active nitrogenase [67]

Acknowledgments The authors sincerely thank the Department of Product Evaluation (Shanghai Jiyan Biomedical Development Co., Ltd.) for their technical support in skin experiments

Instead, Arrowhead launched programs based on the TRiM platform, including ARO-AAT and ARO-HBV (Table 1, Fig