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Front Pharmacol (2021) 12:634822

Cefiderocol, a siderophore cephalosporin from a unique catabolic prodrug class, uses a Trojan horse strategy for the penetration of the outer membrane of Gram-negative bacteria [249]

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Tracleer can restore the activity of pulmonary vascular endothelial cells (ECs) and NOS in rats exposed to hypoxia, promote NO synthesis, resist pulmonary vasoconstriction caused by hypoxia, expand pulmonary arteries, reduce pulmonary artery pressure, and reduce fluid penetration into the alveoli

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