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This unbalanced regulation of the glutathione oxidation/reduction cycle indicates the existence of an alternative pathway to regenerate GSH from GSSG to maintain a stable GSSG/GSH ratio
They can undergo gradual degradation to enable the sustained release of bioactive ions, which exert multiple functions, including interference with tumor cell metabolism and immune regulation
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Organelle transporters define metabolic compartmentalization and how this metabolite transport process can be modulated is poorly explored
