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Assessed through medicinal-chemistry optimization and pathway-level translational frameworks

CAS number: 221231-10-3

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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis

Those with digestive challenges or dietary limitations may also see better results with this approach

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