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Chronic treatment with EGCG (50 and 100 mg/kg, oral gavage 30 min before lipopolysaccharide/ Brucella abortus administration) for 21 days restored the period of immobility, post swim fatigue, thermal hyperalgesia, oxidativenitrosative stress (increased lipid peroxidation, nitrite levels and decreased endogenous antioxidant enzymes such as SOD, GSH and catalase), and inflammatory mediators (increased TNF- and tissue growth factor- (TGF-) levels) in a mouse model of immunologically induced chronic fatigue (Sachdeva et al

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Inject slowly to improve patient comfort and reduce tissue trauma

7,9,13 Nonetheless, these challenges can be addressed by in-situ gel (ISG) systems

[DOI] [PubMed] [Google Scholar] 29.Sikiric P., Buljan M., Vnuk D., Krstonijevic Z., Sever M., Lojo N., Drmic D., Zenko Sever A., Baric M., Starcevic N., et al

Additionally, there is an increase in worldwide obesity due to changes in eating pattern and lifestyle
