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Since SOD and CAT neutralize excess ROS, their reduced activity directly reflects weakened antioxidant capacity and exacerbated ferroptosis

Am J Hum Genet 83: 582593 [DOI] [PMC free article] [PubMed] [Google Scholar] Wonnapinij P, Chinnery PF, Samuels DC 2010
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Additionally, the clinical trial was terminated due to the occurrence of side effects, including impaired dark color adaptation [200, 202]
