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L.FrancheteauM.PrestozL.et al

report (GSE117735) 25 using similar data from the Orlando et al

Numerous candidate targets have been proposed ( Table 2 ), which provide a basis for the precise application of CAR T-cell therapy.The hinge region connects the scFv to the transmembrane domain, providing structural flexibility and facilitating optimal spatial orientation between the CAR and its cognate antigen

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doi: 10.1371/journal.pmed.1001921 24 KohanskiM