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Kennedy AL, Morton JP, Manoharan I, Nelson DM, Jamieson NB, Pawlikowski JS et al

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Upon receptor binding, MT1 triggers the cAMP signaling cascade, upregulating the enzyme tyrosinase and increasing the production of eumelanin the dark, UV-protective form of melanin

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An incisional biopsy was performed, and the histopathologic findings were consistent with malignant melanoma

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