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It only takes about 60 seconds for blood to make a complete trip from your heart, through all your organs, and back again

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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Koc H.C., Xiao J., Liu W., Li Y., Chen G

Once inside the hepatocyte, the passenger strand is degraded and the antisense strand is loaded onto the RNA-induced silencing complex (RISC), which will then detect and degrade PCSK9 mRNA