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Zhang, Hao

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Kassam, I., Wu, Y., Yang, J., Visscher, P

c , d , Gpx4 -deficiency did not significantly affect the growth of melanoma cells cultured in low oxygen ( c ) but did significantly reduce the growth of some melanomas cultured at atmospheric oxygen levels ( d ) ( n = 6 replicate cultures per melanoma

[PubMed: 17717290] 671
Thus, VIC is involved in epigenetic modifications of histones containing the Jumonji-C domain (JHDM) and the ten-eleven translocation (TET) family of DNA hydroxylases
