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Description
Its synthesised by bacteria in the gut of animals and when we eat animal products we ingest it as a byproduct

doi:10.1177/15648265100311S104

"Hypervitaminemia B12 in the Elderly: A Forgotten Marker of Serious Underlying Diseases"
The answer has almost nothing to do with science and almost everything to do with the bureaucratic weirdness of compounding laws

Thus, given the accumulating evidence across species implicating this pathway as integral to aging and its associated diseases, the development of therapeutics aimed at modulating IGF-1 signaling in humans could prove highly effective as a translational tool to delay aging

There may be ways of reducing or preventing them
