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Measurements of serum vitamin B 12 may not reliably detect deficiency, and measurement of serum homocysteine and/or methylmalonic acid should be used to confirm deficiency in asymptomatic high-risk patients with low normal levels of vitamin B 12

Data from the Global Burden of Disease (GBD) study indicate that kidney failure contributes to approximately 11.5% of global cardiovascular mortality (Collaborators, 2025)

This unique characteristic of GSTLs help in the substitution of amino acid in active site residues forming mixed disulfides with thiol group rather than promoting formation of reactive thiolate anion of GSH

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JAMA 328 , 310 (2022)

In the following sections, we discuss those categories and the peptides most often associated with them