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The rationale for combining these two peptides is rooted in their complementary mechanisms of action

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That is, after the initial treatment with injections of B12, dietary supplements of B12 (cyanocobalamin tablets) may be advised instead of injections

When this happens, the characteristic pink color can fade

The requirement for informed consent from the study subjects was waived by the Institutional Review Board due to the retrospective study design (REC 65-293-11-1)