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The Brink: Why are booster shots necessary if the vaccines are working as well as scientists hoped

Certain populations face higher deficiency risk: vegetarians and vegans (B12 is primarily found in animal products), adults over 50 (decreased stomach acid reduces B12 absorption), individuals with digestive disorders like Crohn's disease or celiac disease, and those taking medications like metformin or proton pump inhibitors

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This lack of intrinsic factor decreases the amount the body is able to absorb vitamin B12 after gastric bypass and to a lesser extent after laparoscopic gastric sleeve surgery