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Figure 2 2.1.1 Pro-ferroptotic drivers: ACSL4 and iron Acyl-CoA synthetase long-chain family member 4 (ACSL4) is key determinant of ferroptosis sensitivity

These isomers also inhibit DNA/protein synthesis, promote differentiation and apoptosis, and reverse drug resistance [209], resulting in a synergistic effect greater than the sum of individual actions

Preimmune serum was collected and treated as described above for the DPEP1 serum, before injecting the immunogen

Availability of data and materials The data that support the findings of this study are available from the corresponding author, upon reasonable request

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Salisbury BH, Leslie SW, Tadi P

The metabolic profiles of NADPH in EC senescence and the potential regulatory role of NADPH-related metabolic pathways in vascular aging remain largely unexplored