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Choose a site (abdomen, thigh, or upper arm) and clean it with a fresh alcohol swab, letting it dry fully [11]

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When you drink less water than your body needs, urine becomes more concentrated, making it look dark

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This is likely due to a reduction of peptide interactions (mainly A5 Cagri ) with ECL3 that is a consequence of the engagement of the lipidated N-terminus with the top segment of TM5/ECL2, facilitating flexibility of ECL3