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Description
Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary

Phase 2 NEJM 2023: 24.2% at 48 weeks
MATERIALS AND METHODS Patients Patients with a molecularly confirmed diagnosis of clEDS were identified through the national complex EDS service in London and Sheffield or through collaborations
10.5534/wjmh.210153 61
Confocal fluorescence analysis of SH-SY5Y cells expressing YFP-ArfGAP1 variants reveals that WT ArfGAP1, and to a greater extent the 3A mutant, mostly co-localize with the GM130-labeled Golgi complex, whereas ArfGAP1-3D adopts a distinct cytoplasmic-like localization (Figure 8A)
33 , e300 (2018)
