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Ovarian granulosa cells regulate the accumulation of serotonin in oocytes through the uptake and degradation of serotonin by SERT and monoamine oxidase (MAO), respectively, and granulosa cells form a functional barrier that protects oocytes from exogenous serotonin and may play an important role in oocyte maturation and early embryonic development (Figure 3)

24 To determine whether high-dose folinic acid can improve core and associated ASD symptoms, we conducted a single-site randomized double-blind placebo-controlled clinical trial

Chronic stress predisposes individuals to psychiatric disorders

A prospective randomized clinical trial conducted in Italy in 2017 enrolled 168 patients with HT to evaluate the added benefit of Myo-inositol and selenium co-supplementation

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Jeffers M, Schmidt L, Nakaigawa N, Webb CP, Weirich G, Kishida T, Zbar B, Vande Woude GF

10.3389/fphar.2020.614290 [DOI] [PMC free article] [PubMed] [Google Scholar] 154.A
