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In rheumatoid arthritis (RA), overproduction of the cytokine tumor necrosis factor (TNF) is a central event in pathogenesis, and endoplasmic reticulum (ER) rich T cells are the major releasers of TNF in inflamed joints
322 Mechanistically, the SIRT6-mediated antioxidant effect by H3K56ac deacetylation activated the Nrf2-mediated antioxidant gene
It acts as a powerful antioxidant, combating oxidative stress and supporting numerous bodily functions, including detoxification and immune function
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Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haeme synthesis
