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[Google Scholar] 105.Peskin AV, Winterbourn CC

The experiments outcome confirmed that adipogenesis and inflammatory reaction during 3 T3-L1 cell differentiation could be inhibited by reducing glycerol-3-phosphate dehydrogenase (GPDH) activity and nitric oxide (NO: a plant signal) production, as well as by regulating the expression of genes related to fatty acid synthesis and inflammatory mediators

Collectively, these studies demonstrate the therapeutic potential of combining system x C inhibitors with APR-246 to synergistically target cancer cells with mut-p53 accumulation