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Description
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Work from the Granneman group identified ABHD5 ligands that could stimulate lipolysis by bypassing receptor activation through the dissociation of ABHD5 from PLIN1 (48)

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Intriguingly, another interesting research lead to the discovery of a differential role for IRSs in apoptosis, suggesting an antiapoptotic effect for IRS-2 [122] which is consistent with known differential roles of IGF-1 and insulin
