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Rodent (lean diet combination) Sampson et al

Among the most frequently reported adverse effects are minor and self-limiting such as local injection site erythema, transient hormonal shifts, and receptor desensitization with prolonged or high-frequency use

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It has been extensively studied for its regenerative effects, particularly in healing soft tissue, reducing inflammation, and improving gut health
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If standardized peptide formulations can be verified and administered within controlled protocols, these agents may represent a future adjunct to evidence-based perioperative care, particularly in populations undergoing TJA where wound healing, metabolic health, and inflammatory regulation strongly influence outcomes
