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a-c , Autochthonous tumors from MMTV-PyMT Gclc f/f Rosa26-CreERT2 mice were excised and subcutaneously transplanted into flanks of wild-type C57BL/6 mice, which were treated with vehicle (corn oil

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Collectively, these findings demonstrate that SLE is characterized by mTOR pathway hyperactivation and distinct T cell metabolic reprogramming favoring glycolysis and FAS, which disrupts Th17/Treg balance and drives autoimmunity, positioning metabolic intervention as a viable treatment strategy

doi: 10.1210/er.2013-1071 78 FrystykJIvarsenPSkjaerbaekCFlyvbjergAPedersenEBOrskovH

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