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Side Effects & Mitigation Because there is no completed human safety trial, the honest statement is that the human side-effect profile is not well characterised

Patients following such a diet, should be advised to take oral vitamin B 12 regularly

Some chemotherapy drugs or antiretroviral medications (for HIV) that suppress bone marrow might also blunt the effectiveness of B therapy

They support cognitive function and can help reduce feelings of irritability and anxiety, promoting a balanced mood

Declining NAD+ impairs energy, metabolism, skin health, and immunity, accelerating biological aging.[12][13] Research indicates that this loop can be interrupted by boosting NAD+, potentially reversing aspects of biological age as measured by epigenetic clocks

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