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Complementary therapies in clinical practice

The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)

Deficiency of B12 occurs due to inadequate intake, decreased consumption of meat and dairy products, low intrinsic factor and malabsorption due to gastrectomy

This is a mechanistic limitation, not a flaw unique to AOD-9604

Improves energy metabolism to ensure the efficient release of energy necessary for optimal muscle function and optimal oxygen carrying capacity of red blood cells for muscle perfusion

Volume 4, Number 3, June 2014, pages 64-77 Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R