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Description
Using bioinformatics tools, a mapping was created between these 560 genes and drugs in publicly available DrugBank and STITCH databases
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GLS inhibition with CB-839 successfully targets GLS-expressing cells
Cao W, Meng Q, Yiting W, Qingyan Y, Zhangchunzi Z, Xiaodong N, Zhongwu L
PMC 17835
31 This modification can trigger alterations in DNA conformation, DNA stability, chromatin structure, and the interplay between DNA and proteins, thereby exerting a regulatory influence on gene transcription
