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This manuscript was published from Joses graduate research, he graduated from the PGE department last year, and is now working for Vaulted Deep.

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doi: 10.1002/msb.20134892 98 MengaAFaviaMSperaIVeglianteMCGissiRDe GrassiAet al

TLR3 detects double-stranded RNA (dsRNA) [21], TLR7 and TLR8 recognise single-stranded RNA (ssRNA) [22], and TLR9 is activated by DNA containing unmethylated CpGs which are abundant in microbial but rare in vertebrate genomes (i.e., 6090% of mammalian CpGs are methylated) [23,24]