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doi: 10.1042/CS20180315

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If your vitamin B12 deficiency is not caused by a lack of vitamin B12 in your diet, youll usually need to have an injection of hydroxocobalamin every 2 to 3 months for the rest of your life
Trials continue even after approval

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Intramuscular injections are often more effective than oral supplements for severe deficiencies or neurological symptoms, as they deliver B12 directly into your bloodstream and bypass absorption issues