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The most common cause of methaemoglobinaemia is exposure to an oxidising agent, such as in nitrite poisoning, however it can also be caused by a variety of genetic defects affecting both red cell metabolism and Hb structure 3

NAC Antioxidant Administration After 5 weeks on the diets, females underwent antioxidant treatment with NAC (or tap water as control), for 5 weeks, until the end of dietary treatment

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Antioxid Redox Signal 10:194188 Manevich Y, Feinstein SI, Fisher AB (2004) Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with pi GST

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Antioxidant intake is associated with semen quality in healthy men